CardioGenomic Profile
The CardioGenomic Profile test evaluates
genetic variations (SNPs) in genes that modulate blood pressure
regulation, lipid balance, nutrient metabolism, inflammation,
and oxidative stress.
The CardioGenomic test
uncovers potential genetic susceptibility to:
- Hypercholesteremia
- Myocardial Infarction
- Atherosclerosis
- Thromboses
- Obesity
- Endothelial Dysfunction
- Hypertension
- Stroke
- Coronary Artery Disease
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CardioGenomic Tests for Cholesterol Regulation and
Atherosclerosis
- ApoE (apoliprotein E)
- CETP (cholesteryl ester transfer protein)
- SELE (selectin E)
These genes affect how the body breaks down and clears fats
and how cholesterol is processed. They also affect lipid
balance, plaque formation, and blood vessel integrity and
function.
CardioGenomic Tests for Methylation
- MTHFR (methylenetetrahydrofolate reductase)
Polymorphisms of this enzyme can disrupt the metabolism of
homocysteine, resulting in its accumulation as well as impaired
methylation. The presence of these SNPs can increase risk of
cardiovascular disease, blood vessel damage, thromboses (blood
clots), stroke, and degenerative aging.
CardioGenomic Tests for Hypertension
- GNB3 (guanine nucleotide-binding protein)
- AGT (angiotensin)
- AGTR1 (angiotensin II receptor–1)
Polymorphisms of these genes are associated with blood
vessel constriction, sodium and water retention, obesity, and
increased susceptibility to hypertension.
CardioGenomic Tests for Coagulation
- Factor 2 (prothrombin)
- Factor 5 (Leiden)
These genetic variants can over-activate blood clotting
processes, increasing the risk of sudden cardiac events such as
thromboses, heart attacks, and strokes.
CardioGenomic Tests for Reduction-Oxidation
Balance
- CYBA*8 (cytochrome b-245-alpha)
This genetic variant mediates the balance between oxidative
stress and antioxidant defense in smooth muscle cells lining
blood vessels.
CardioGenomic Profile Description
CardioGenomic Profile Sample Report
CardioGenomic Kit Instructions
Sample Requirement: Mouth Rinse or Blood Draw
Sorry, Genovations Genomic Tests are not available
in New York.
Turn around time is 21 days.
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