RejuveSolution™ Science
The science behind RejuveSolution support for hair growth, nail growth, wrinkle treatment,
osteoporosis and arthritis.
RejuveSolution uses a patented process that prohibits silica from turning
into a polymer as silica does in other supplements (i.e. gels, horsetail herb), rendering superior
absorption.
RejuveSolution contains choline, a nutrient especially important to membrane health. Choline is
combined with elemental silicon to yield a stabilized, well absorbed form of silica.
Silica exists in a variety of forms in nature and its component, silicon is the second most
prevalent element after oxygen.1 Orthosilicic acid, (H4SiO4) a water-soluble form of silicic acid
found in very dilute concentration in the earth’s waters, is the form humans predominantly absorb and is found in
the serum fraction of blood. In its non-polymerized form, silicon is very unstable; thus making it available for
supplementation has been difficult.
Compelling data supports a myriad of health benefits of adequate silica. The benefits are
undoubtedly due to silica’s ability to activate the body’s synthesis of collagen which constitutes one-third of the
body’s protein.
A study demonstrated a 12.5% increase in collagen in the skin with ch-OSA
supplementation.2 Silica supplementation stimulates collage type-1 synthesis in osteoblasts,
enhances osteoblast differentiation,3 increases calcium uptake4 and is a major
determinant in bone mineral density in men and pre-menopausal women.5
In addition to collagen, silica has a role in the synthesis of two other "beauty proteins" -
elastin and keratin.2 Silica deficiency may cause bone and joint deformities and disrupt mineral
balance.1
Another 20-week, randomized, double blind, placebo-controlled study with 50 women with
photo-damaged facial skin showed oral intake of 10 mg ch-OSA, found in 2 capsules of Rejuvesolution, resulted in a
30% reduction in micro-wrinkle depth, compared to placebo, and 30% reduction in skin roughness and a positive
effect on brittleness of hair and nails.6
In a nine-month, randomized, double-blind, placebo-controlled trial with 48 healthy Caucasian
women with fine hair (average age 43.3 years), an international research team concluded that ch-OSA (5 mg ch-OSA
twice daily) safely and significantly improved hair fiber thickness and helped reduce loss of hair elasticity and
strength. Orthosilicic acid delivered by ch-OSA is known to bind with positively charged amino-groups in peptides.
This structural interaction might improve the mechanical properties of keratin resulting in improved hair tensile
properties.7

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RejuveSolution help's your body make the beauty proteins collagen, keratin and elastin.
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The science behind RejuveSolution
support for hair growth, nail growth, wrinkle treatment, osteoporosis and arthritis.
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RejuveSolution Supplement Facts Label, Ingredient List and Dosing.
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RejuveSolution Dosage Information is Based on Scientific Research Studies.
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RejuveSolution Literature
RejuveSolution literature and information supporting it's use for hair growth, wrinkles, nail growth,
osteoporosis and arthritis.
References
1. Martin KR. The chemistry of silica and its potential health benefits. J Nutr
Health Aging. 2007 Mar-Apr;11(2):94-7. [PMID: 17435951]
2. Calomme MR, Vanden Berghe DA. Supplementation of calves with stabilized
orthosilicic acid. Effect on the Si, Ca, Mg, and P concentrations in serum and the collagen concentration in skin
and cartilage. Biol Trace Elem Res. 1997 Feb;56(2):153-65 [PMID: 9164661]
3. Reffitt DM, et al. Orthosilicic acid stimulates collagen type 1 synthesis and
osteoblastic differentiation in human osteoblast-like cells in vitro. Bone. 2003 Feb;32(2):127-35 [PMID:
12633784]
4. Calcif Tissue Int 2002;70:292, P-139
5. Jugdaohsingh R, et al. Dietary silicon intake is positively associated with bone
mineral density in men and premenopausal women of the Framingham Offspring cohort. Bone 2003 May;32,:S192 [PMID:
14969400]
6. Barel A, et al. Effect of oral intake of choline-stabilized orthosilicic acid on
skin, nails and hair in women with photodamaged skin. Arch Dermatol Res. 2006 Feb;297(8):381 [PMID:
16205932]
7. Wickett RR, Effect of oral intake of choline-stabilized orthosilicic acid on
hair tensile strength and morphology in women with fine hair. Arch Dermatol Res. 2007 Dec;299(10):499-505. [PMID:
17960402]
8. Silicon: http://nhiondemand.com {accessed 18 Dec 2008}
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