CardioGenomic Profile
The CardioGenomic Profile test evaluates genetic variations (SNPs) in genes that modulate blood
pressure regulation, lipid balance, nutrient metabolism, inflammation, and oxidative stress.
The CardioGenomic test uncovers potential genetic susceptibility
to:
- Hypercholesteremia
- Myocardial Infarction
- Atherosclerosis
- Thromboses
- Obesity
- Endothelial Dysfunction
- Hypertension
- Stroke
- Coronary Artery Disease
CardioGenomic Tests for Cholesterol Regulation and Atherosclerosis
- ApoE (apoliprotein E)
- CETP (cholesteryl ester transfer protein)
- SELE (selectin E)
These genes affect how the body breaks down and clears fats and how cholesterol is processed. They also affect
lipid balance, plaque formation, and blood vessel integrity and function.
CardioGenomic Tests for Methylation
- MTHFR (methylenetetrahydrofolate reductase)
Polymorphisms of this enzyme can disrupt the metabolism of homocysteine, resulting in its accumulation as well
as impaired methylation. The presence of these SNPs can increase risk of cardiovascular disease, blood vessel
damage, thromboses (blood clots), stroke, and degenerative aging.
CardioGenomic Tests for Hypertension
- GNB3 (guanine nucleotide-binding protein)
- AGT (angiotensin)
- AGTR1 (angiotensin II receptor–1)
Polymorphisms of these genes are associated with blood vessel constriction, sodium and water retention, obesity,
and increased susceptibility to hypertension.
CardioGenomic Tests for Coagulation
- Factor 2 (prothrombin)
- Factor 5 (Leiden)
These genetic variants can over-activate blood clotting processes, increasing the risk of sudden cardiac events
such as thromboses, heart attacks, and strokes.
CardioGenomic Tests for Reduction-Oxidation Balance
- CYBA*8 (cytochrome b-245-alpha)
This genetic variant mediates the balance between oxidative stress and antioxidant defense in smooth muscle
cells lining blood vessels.
CardioGenomic Profile Description
CardioGenomic Profile Sample Report
CardioGenomic Kit Instructions
Sample Requirement: Mouth Rinse or Blood Draw
Sorry, Genovations Genomic Tests are not available in New York.
Turn around time is 21 days.
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